J Cardiothorac Surg. 2026 May 6. doi: 10.1186/s13019-026-04256-w. Online ahead of print.ABSTRACTOBJECTIVE: Patients with chronic coronary syndrome (CCS) make up a large portion of those undergoing coronary artery bypass grafting (CABG), and there are significant gaps in the evidence regarding the op
BMJ Open. 2026 May 6;16(5):e113927. doi: 10.1136/bmjopen-2025-113927.ABSTRACTINTRODUCTION: Recovery after extremity fracture is influenced by injury-related impairments, functional capacity, symptom severity and psychosocial well-being, emphasising the need for patient-reported outcome measures (PRO
J Clin Med. 2026 Apr 18;15(8):3102. doi: 10.3390/jcm15083102.ABSTRACTOver the past years, burn care has evolved from a discipline focused on survival to one centered on restoring long-term health, function, and quality of life. Significant advances in critical care, early excision and grafting, infe
J Clin Med. 2026 Apr 8;15(8):2822. doi: 10.3390/jcm15082822.ABSTRACTBackground/Objectives: Reconstruction of orbital floor fractures remains surgically challenging due to limited intraoperative visibility and complex anatomy. Inaccurate implant placement often leads to persistent complications and t
EFORT Open Rev. 2026 May 1;11(5):366-371. doi: 10.1530/EOR-2026-0055.ABSTRACTThe European Union Medical Device Regulation (MDR 2017/745) has introduced stricter requirements for clinical evidence, limited reliance on equivalence and expanded post-market surveillance for orthopaedic implants. While d
Mol Neurobiol. 2026 Apr 29;63(1):595. doi: 10.1007/s12035-026-05877-x.ABSTRACTThe current management of neurological disorders remains largely symptomatic. In recent years, stem cell-derived exosomes have emerged as a promising alternative therapeutic strategy. This narrative review synthesizes evid
J Neurooncol. 2026 Apr 28;177(3):131. doi: 10.1007/s11060-026-05589-1.ABSTRACTBACKGROUND: The management of vestibular schwannoma (VS) has traditionally prioritized gross total resection to achieve high tumor control, often at the cost of cranial nerve injuries and quality of life impairment. Howeve
J Vis Exp. 2026 Apr 10;(230). doi: 10.3791/70216.ABSTRACTVascularized composite allotransplantation (VCA) is increasingly recognized as a reconstructive option that offers substantial benefits for patients with severe tissue loss, including injuries affecting the face and hand. Despite its clinical
Ann Chir Plast Esthet. 2026 Apr 24:S0294-1260(26)00034-8. doi: 10.1016/j.anplas.2026.02.004. Online ahead of print.ABSTRACTChronic wounds represent a significant healthcare challenge, necessitating innovative regenerative approaches. Autologous skin micrografts (ASMs) offers a promising solution for
Spine (Phila Pa 1976). 2026 Apr 21. doi: 10.1097/BRS.0000000000005710. Online ahead of print.ABSTRACTSTUDY DESIGN: Literature review and international cross-sectional survey with Rasch psychometric analysis.OBJECTIVE: To evaluate the clinical, economic, and operational impact of navigation and robot
Pain Manag. 2026 Apr 23:1-13. doi: 10.1080/17581869.2026.2660326. Online ahead of print.ABSTRACTOBJECTIVE: This study explored patient experiences with non-traumatic painful upper-extremity conditions (NPUCs) and co-occurring risky substance use and assessed perspectives on the acceptability and usa
Chronic Dis Transl Med. 2026 Jan 15;12(1):69-72. doi: 10.1002/cdt3.70034. eCollection 2026 Mar.ABSTRACTWhat's New?: This study introduces a novel, periosteum-preserving iliac crest transverse transport (ICTT) technique for high-level lower extremity arteriosclerosis obliterans (LEASO), targeting pat
Bioeng Transl Med. 2025 Oct 2;11(2):e70065. doi: 10.1002/btm2.70065. eCollection 2026 Mar.ABSTRACTOver the past two decades, an increasing body of evidence has underscored the significant role of the mechanical properties of biological tissues in maintaining tissue functions and regulating cellular
Orthop J Sports Med. 2026 Apr 16;14(4):23259671261422713. doi: 10.1177/23259671261422713. eCollection 2026 Apr.ABSTRACTBACKGROUND: High-grade fracture of the posterolateral tibial plateau (PLTP) has been reported to increase bone loss, which in turn is associated with residual rotational instability
Sci Rep. 2026 Apr 21. doi: 10.1038/s41598-026-49055-4. Online ahead of print.ABSTRACTThe development of physiologically relevant in vitro vascular models requires access to the cellular components of the microvascular niche. However, most studies rely on a limited subset of vascular or support cells
Future Sci OA. 2026 Dec;12(1):2658207. doi: 10.1080/20565623.2026.2658207. Epub 2026 Apr 20.ABSTRACTChondrocyte hypertrophy is a pivotal biological process in skeletal development and disease progression, with its precise regulation being essential for maintaining cartilage homeostasis and promoting
Orthop Surg. 2026 May;18(5):1020-1028. doi: 10.1111/os.70322. Epub 2026 Apr 19.ABSTRACTOBJECTIVE: Distal radioulnar joint (DRUJ) instability is commonly assessed clinically via physical examination, such as a ballottement test, which evaluates palmar-dorsal translation of the radius relative to the
Theranostics. 2026 Mar 30;16(10):5770-5787. doi: 10.7150/thno.126710. eCollection 2026.ABSTRACTBACKGROUND: As a main component of the tissue microenvironment, the extracellular matrix (ECM) provides an instructive niche that regulates stem cell differentiation. Biomimetic ECM collagen hydrogels have
J Hand Surg Am. 2026 Apr 16:S0363-5023(26)00227-3. doi: 10.1016/j.jhsa.2026.03.004. Online ahead of print.ABSTRACTCarpal tunnel syndrome is the most common upper-extremity compressive neuropathy, resulting from increased pressure within the carpal tunnel leading to symptomatic median nerve dysfuncti
Knee Surg Sports Traumatol Arthrosc. 2026 Apr 16. doi: 10.1002/ksa.70398. Online ahead of print.ABSTRACTPURPOSE: As a common chronic joint disease, osteoarthritis (OA) represents a significant public health challenge. Analysing its burden is important for its prevention, treatment and policy develop
Orphanet J Rare Dis. 2026 Apr 14;21(1):149. doi: 10.1186/s13023-026-04341-2.ABSTRACTBACKGROUND: Although individual rare and complex diseases (RDs) affect small patient populations, together they impact an estimated 27–36 million people across the European Union. Addressing this major public health
Molecules. 2026 Mar 28;31(7):1119. doi: 10.3390/molecules31071119.ABSTRACTThe active constituents of essential plant oils (EOAIs), monoterpenoid carvacrol and monoterpene p-cymene, are widely distributed in many aromatic plants and their products. They differ in that carvacrol has a phenolic functio
Clin Exp Allergy. 2026 May;56(5):476-497. doi: 10.1111/cea.70251. Epub 2026 Apr 13.ABSTRACTBACKGROUND: Heterogeneity in outcome reporting and inconsistent use of outcome measurement instruments in allergy and clinical immunology research affects the comparability, synthesis, and clinical applicabili
Crit Rev Oncol Hematol. 2026 Apr 12;223:105337. doi: 10.1016/j.critrevonc.2026.105337. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) ranks among the most prevalent and lethal malignancies worldwide. The majority of patients are diagnosed at advanced stages, where current targeted ther
