J Hand Microsurg. 2025 Nov 25;18(1):100390. doi: 10.1016/j.jham.2025.100390. eCollection 2026 Jan.ABSTRACTThree-dimensional (3D) technology has rapidly evolved from an innovative concept into an essential surgical tool. The increasing availability of high-resolution imaging, affordable 3D printers a
Ann Ital Chir. 2025 Oct 29;96(12):1592-1612. doi: 10.62713/aic.3943.ABSTRACTAIM: Hirschsprung's disease, or aganglionosis of the colon, is a congenital disease characterized by a lack of neurons in the enteric plexus of the large bowel due to either migration failure or defective differentiation of
Nat Commun. 2025 Dec 15. doi: 10.1038/s41467-025-67641-4. Online ahead of print.ABSTRACTNuclear Factor IA, a member of the long-studied Nuclear Factor I family of DNA-binding proteins, plays pivotal roles in development and metabolism. Dysregulation or loss of Nuclear Factor IA is associated with se
Plast Reconstr Surg. 2025 Dec 16. doi: 10.1097/PRS.0000000000012717. Online ahead of print.ABSTRACTA clear understanding of the various dimensions and applications of available screws used in hand surgery is critical for the effective management of fractures, osteotomies, and arthrodeses. In 2015, a
J Arthroplasty. 2025 Aug 26:S0883-5403(25)00954-4. doi: 10.1016/j.arth.2025.07.052. Online ahead of print.ABSTRACTThe integration of artificial intelligence (AI), the rise of mega-journals, and the manipulation of impact factors present challenges to scientific integrity. These trends threaten the c
Adv Healthc Mater. 2025 Dec 12:e03972. doi: 10.1002/adhm.202503972. Online ahead of print.ABSTRACTDespite remarkable advancements in hydrogel-based medical applications in recent years, their clinical translation for pancreatic fistula management remains challenging owing to the moist surgical envir
Cell Death Dis. 2025 Dec 12;16(1):887. doi: 10.1038/s41419-025-08222-7.ABSTRACTTumors have a unique niche system that plays an important role in their occurrence and development. At present, there is increasing interest in the biomechanical properties of niches. The increased stemness of cancer cell
Disabil Rehabil. 2025 Dec 12:1-15. doi: 10.1080/09638288.2025.2598382. Online ahead of print.ABSTRACTPURPOSE: Post-surgical rehabilitation may benefit patients after distal radius fractures, yet evidence guiding referral to supervised versus home-based rehabilitation remains unclear. Shared decision
Plast Reconstr Surg Glob Open. 2025 Dec 8;13(12):e7109. doi: 10.1097/GOX.0000000000007109. eCollection 2025 Dec.ABSTRACTBACKGROUND: Body contouring is an increasingly common trend in aesthetic plastic surgery. In the pursuit of ideal body proportions, anterior thoracic cage deformities, especially l
Cancer. 2025 Dec 1;131 Suppl 3:e70149. doi: 10.1002/cncr.70149.ABSTRACTBACKGROUND: Although therapeutic drug monitoring is crucial for the comprehensive management of gastrointestinal stromal tumors (GISTs), the relationship between plasma concentration of ripretinib and its therapeutic efficacy is
J Hand Microsurg. 2025 Nov 19;18(1):100385. doi: 10.1016/j.jham.2025.100385. eCollection 2026 Jan.ABSTRACTAnatomic total shoulder arthroplasty (TSA) has advanced considerably in recent decades, with the glenoid component recognized as a pivotal determinant of patient outcomes. This review integrates
J Hand Surg Glob Online. 2025 Nov 21;8(1):100888. doi: 10.1016/j.jhsg.2025.100888. eCollection 2026 Jan.ABSTRACTPURPOSE: Some variation in presurgical care is inevitable, yet it represents an understudied opportunity to improve the value and standardization of care leading up to surgery. This study
J Hand Surg Eur Vol. 2025 Dec 7:17531934251403333. doi: 10.1177/17531934251403333. Online ahead of print.ABSTRACTConflicts of interest (COI) are pervasive in hand surgery, where clinical practice, research, and education intersect with industry. Beyond financial ties, COIs can be research-related, p
Pharm Res. 2025 Dec 5. doi: 10.1007/s11095-025-03975-4. Online ahead of print.ABSTRACTBACKGROUND: The beginning of precision medicine has come to rise in a new era of targeted therapies. Among these innovations, light-activatable antibody photo drug conjugates/photoimmunoconjugates termed as "PhotoB
Bioact Mater. 2025 Nov 20;57:531-550. doi: 10.1016/j.bioactmat.2025.10.040. eCollection 2026 Mar.ABSTRACTNeuromodulatory signals play a critical role in initiating early vascularized bone regeneration following bone injury. Despite advancements in bone tissue engineering centered on mesenchymal stem
Adv Healthc Mater. 2025 Dec 3:e03768. doi: 10.1002/adhm.202503768. Online ahead of print.ABSTRACTThoracic aortic dissection (TAD), a lethal cardiovascular emergency, lacks effective pharmacological interventions. Endothelial dysfunction and hydrogen sulfide (H2S) deficiency drive TAD progression, bu
NPJ Aging. 2025 Dec 1. doi: 10.1038/s41514-025-00302-4. Online ahead of print.ABSTRACTPremature ovarian insufficiency (POI) is one of the most common diseases contributing to declining fertility globally. Autoimmune dysregulation has been implicated in POI, but the role of B cell and its subsets in
Biofilm. 2025 Nov 5;10:100324. doi: 10.1016/j.bioflm.2025.100324. eCollection 2025 Dec.ABSTRACTBiofilms, complex microbial communities that enhance pathogen survival in hostile environments, are integral to chronic infections and often exhibit polymicrobial interactions that influence disease outcom
Cent European J Urol. 2025;78(3):394-400. doi: 10.5173/ceju.2025.0092. Epub 2025 Aug 31.ABSTRACTINTRODUCTION: To evaluate the intrarenal pressure parameters of the 9.2 Fr (5.1 Fr working channel) and 7.5 Fr (3.6 Fr working channel) flexible ureteroscopes with direct-in-scope suction (DISS) in an ex
Plast Reconstr Surg Glob Open. 2025 Nov 25;13(11):e7309. doi: 10.1097/GOX.0000000000007309. eCollection 2025 Nov.ABSTRACTBACKGROUND: ChatGPT, a large language model artificial intelligence (AI), has been used to augment patient-facing information, aid in resident education, and support research ende
J Cachexia Sarcopenia Muscle. 2025 Dec;16(6):e70128. doi: 10.1002/jcsm.70128.ABSTRACTCachexia, a syndrome marked by nonintentional weight loss, muscle wasting, functional decline and poor prognosis, affects 50%-80% of cancer patients, severely impacting quality of life, treatment tolerance and survi
J Hand Surg Eur Vol. 2025 Nov 26:17531934251383073. doi: 10.1177/17531934251383073. Online ahead of print.ABSTRACTINTRODUCTION: Trapeziometacarpal joint stability during pinch depends on the balance between the opponens pollicis and the first dorsal interosseous muscles, which control pronation and
Sci Rep. 2025 Nov 26. doi: 10.1038/s41598-025-30155-6. Online ahead of print.ABSTRACTThis cross-sectional study investigated the prevalence of work-related musculoskeletal disorders (WMSDs), ergonomic risks, and psychosocial factors among 99 office workers at an industrial company. Participants, age
Burns. 2025 Nov 11;52(1):107777. doi: 10.1016/j.burns.2025.107777. Online ahead of print.ABSTRACTBACKGROUND: Acute burns and their sequelae in the axilla are debilitating injuries. Reconstruction in this anatomically complex region is challenging due to limited tissue availability and the need to ba
