Acta Pharm Sin B. 2025 May;15(5):2655-2672. doi: 10.1016/j.apsb.2025.03.046. Epub 2025 Apr 4.ABSTRACTSonodynamic therapy (SDT) can potentially induce immunogenic cell death in tumor cells, leading to the release of ATP, and facilitating the initiation of an immune response. Nevertheless, the enzymes
Sci Rep. 2025 Jun 6;15(1):20025. doi: 10.1038/s41598-025-02536-4.ABSTRACTCollagen is critical to the structure and function of skin tissues, with the collagen I/III ratios influencing fibrillogenesis, fiber organization, and skin mechanics. Abnormal collagen organization, such as in fibrosis or scar
J Oral Maxillofac Surg. 2025 May 21:S0278-2391(25)00291-5. doi: 10.1016/j.joms.2025.05.008. Online ahead of print.ABSTRACTBACKGROUND: Virtual surgical planning (VSP) for composite microvascular free flaps has become the standard-of-care for oncologic head and neck reconstruction. Controversy remains
Acta Biomater. 2025 Jun 2:S1742-7061(25)00406-4. doi: 10.1016/j.actbio.2025.05.072. Online ahead of print.ABSTRACTAdhesion is a common complication during healing of injured tendons. TGF-β1 has a dual role in tendon healing, which is promoted in the early stages, while continued expression in the mi
Lung Cancer. 2025 Jun 1;205:108594. doi: 10.1016/j.lungcan.2025.108594. Online ahead of print.ABSTRACTLung cancer is the most frequently diagnosed malignancy worldwide and remains the leading cause of cancer-related mortality. Non-small-cell lung cancer (NSCLC) is the most prevalent type of lung can
Biomed Eng Online. 2025 Jun 3;24(1):68. doi: 10.1186/s12938-025-01371-y.ABSTRACTGastrointestinal malignancies present a significant menace to the well-being of people across the globe. Consequently, the prompt and precise identification of such tumors is of utmost importance. Biosensor technology em
Ann Plast Surg. 2025 Jun 1;94(6S Suppl 4):S564-S567. doi: 10.1097/SAP.0000000000004387.ABSTRACTINTRODUCTION: Current management via open dissection for cubital tunnel syndrome is efficacious; however, it can lead to lengthy recovery. Sonography can be utilized in open dissections for cubital tunnel
Am Surg. 2025 Jun 2:31348251346539. doi: 10.1177/00031348251346539. Online ahead of print.ABSTRACTArtificial Intelligence (AI) is transforming surgical education, playing a pivotal role in the era of digital surgery. This review, conducted from January 2023 to December 2024, examines the integration
J Biomech. 2025 Apr 16;188:112703. doi: 10.1016/j.jbiomech.2025.112703. Online ahead of print.ABSTRACTThe distal radioulnar joint (DRUJ) is a load-bearing joint that permits pronosupination of the forearm. Pronosupination may provoke instability following injuries to the soft tissue stabilizers of t
Arthroplasty. 2025 May 30;7(1):31. doi: 10.1186/s42836-025-00308-z.ABSTRACTAIMS: This study aimed to assess whether the clinical outcomes of one-stage revision surgery for chronic knee periprosthetic joint infection (kPJI), guided by precision pathogen diagnosis strategies, are non-inferior to those
Infect Drug Resist. 2025 May 24;18:2663-2672. doi: 10.2147/IDR.S501740. eCollection 2025.ABSTRACTPURPOSE: This study aims to investigate the antibiotic resistance and virulence factors of Paenibacillus campinasensis, an understudied opportunistic pathogen, through whole-genome sequencing and resista
Orthop Surg. 2025 May 29. doi: 10.1111/os.70085. Online ahead of print.ABSTRACTAccurate alignment correction is closely correlated with functional results after corrective osteotomy for knee joint deformities. Traditionally, osteotomy procedures were performed on the basis of the surgeon's experienc
Wound Repair Regen. 2025 May-Jun;33(3):e70049. doi: 10.1111/wrr.70049.ABSTRACTDelayed wound healing and non-healing wounds are common in diabetic patients due to the hostile microenvironments and complex pathophysiology of diabetic wounds. Addressing these challenges remains a significant concern fo
Blood Purif. 2025 May 28:1-25. doi: 10.1159/000545121. Online ahead of print.ABSTRACTFluid overload (FO) is a prevalent and serious complication of end-stage chronic kidney disease (ESRD). Its most dramatic manifestation is acute and life-threatening pulmonary oedema. It is also associated with a hi
Front Neurol. 2025 May 13;16:1587632. doi: 10.3389/fneur.2025.1587632. eCollection 2025.ABSTRACTThe underrepresentation of women and racial minorities in clinical trials populations remains a persistent challenge across many medical specialties, including Neurosurgery. A diverse research cohort brin
J Clin Med. 2025 May 19;14(10):3558. doi: 10.3390/jcm14103558.ABSTRACTBackground/Objectives: Sagittal split ramus osteotomy (SSRO) is a commonly performed procedure in orthognathic surgery. Despite its effectiveness, surgical site infections (SSI) represent a significant postoperative complication,
J Clin Med. 2025 May 14;14(10):3428. doi: 10.3390/jcm14103428.ABSTRACTThe first web space of the hand plays a fundamental role in daily hand function, facilitating crucial movements, such as pinching, grasping, and opposition. The structural anomalies of acquired defects of this anatomical region, w
Cancers (Basel). 2025 May 15;17(10):1668. doi: 10.3390/cancers17101668.ABSTRACTUpper tract urothelial carcinoma (UTUC) is a rare malignancy, representing only 5-10% of urothelial carcinoma. The mainstay of treatment for high-risk patients is radical nephroureterectomy. Given the aggressive behavior
Biomedicines. 2025 May 20;13(5):1239. doi: 10.3390/biomedicines13051239.ABSTRACTBackground/Objectives: The body's reaction after the implantation of a biomaterial is a non-specific inflammatory response that is mainly initiated via the recruitment of polymorphonuclear cells (PMNs) to the implant sit
J Funct Biomater. 2025 May 8;16(5):167. doi: 10.3390/jfb16050167.ABSTRACTIn adults, scars are formed after deep skin wound injuries like burns. However, the fetal microenvironment allows for scarless skin regeneration. One component that is abundantly present in the fetal extracellular matrix is hya
Front Bioeng Biotechnol. 2025 May 12;13:1595772. doi: 10.3389/fbioe.2025.1595772. eCollection 2025.ABSTRACTLiver cancer remains a major global health challenge, characterized by high mortality and limited treatment efficacy. Conventional therapies, including chemotherapy, immunotherapy, and viral ve
Discov Oncol. 2025 May 26;16(1):931. doi: 10.1007/s12672-025-02653-6.ABSTRACTBACKGROUND: Immunoglobulin lambda constant 1 (IGLC1) has been implicated in cancer progression, but its role in osteosarcoma remains unclear. This study endeavored to explore the levels of IGLC1 expression, its implications
Acta Biomater. 2025 May 24:S1742-7061(25)00387-3. doi: 10.1016/j.actbio.2025.05.060. Online ahead of print.ABSTRACTCalcium (Ca²⁺) regulation assumes a critical role in the repair course of peripheral nerve injury (PNI). However, effective calcium sources capable of providing sustained Ca²⁺ signals t
Sci Rep. 2025 May 25;15(1):18185. doi: 10.1038/s41598-025-03296-x.ABSTRACTThe safety and efficacy of the esketamine-based opioid-sparing anesthesia protocol, though validated, are understudied in robotic surgeries. This study used robot-assisted nephrectomy in Bama miniature pigs to explore its appl
