Quantifying Nuance within Sepsis-Associated Immune Suppression toward Diagnostic Certainty

Scritto il 30/10/2025
da Charles C Caldwell

Shock. 2025 Oct 21. doi: 10.1097/SHK.0000000000002745. Online ahead of print.

ABSTRACT

Impact of sepsis on human T-cell function and outcome was assessed. In sepsis survivors, IFNγ-production in response to T-cell stimulation remains intact, while sepsis non-survivors display exaggerated IFNγ responses to TCR-independent stimuli.

PMID:41166166 | DOI:10.1097/SHK.0000000000002745