Cureus. 2026 Mar 16;18(3):e105352. doi: 10.7759/cureus.105352. eCollection 2026 Mar.
ABSTRACT
Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an uncommon autosomal dominant disorder associated with primary hyperparathyroidism due to parathyroid adenomas and ossifying jaw tumors. We present the case of a 31-year-old male who was incidentally diagnosed with severe parathyroid hormone-dependent hypercalcemia following a traumatic upper limb fracture. Subsequent evaluation confirmed the diagnosis of HPT-JT syndrome. Early recognition, prompt surgical management, and genetic confirmation are essential to ensure appropriate treatment and prevent long-term complications.
PMID:42005270 | PMC:PMC13084162 | DOI:10.7759/cureus.105352